CJC-1295 (No DAC) / Ipamorelin — Dual-Peptide Research Formulation
CJC-1295 (without DAC) combined with Ipamorelin is a dual-peptide research formulation that pairs a modified growth hormone-releasing hormone (GHRH) analog with a selective growth hormone secretagogue receptor (GHS-R) agonist. This combination has become a widely studied model in neuroendocrine research, as the two peptides engage complementary signaling pathways that converge on somatotroph function. CJC-1295 without DAC (also known as Mod GRF 1-29) is a truncated and amino acid-substituted GHRH analog designed for enhanced metabolic stability, while Ipamorelin is a pentapeptide ghrelin mimetic with high selectivity for the GHS-R1a receptor subtype.
In vitro studies have demonstrated that simultaneous activation of both GHRH and GHS-R pathways produces synergistic enhancement of cAMP accumulation and intracellular calcium mobilization in pituitary cell models, offering researchers a valuable experimental system for studying receptor crosstalk and signal integration. This formulation is also employed in studies examining dose-response characteristics, temporal kinetics of combined receptor stimulation, and the downstream transcriptional consequences of coordinated pathway engagement in neuroendocrine cell systems.
The product is supplied as a lyophilized peptide blend, with each component independently verified for identity and purity through HPLC and mass spectrometric analysis. Coffee & Pepper Peptides provides this combination reagent for use by qualified scientists conducting investigational studies. It is not intended for human consumption, clinical application, or any purpose other than controlled laboratory research.
FDA DISCLAIMER
The information provided on this website has not been evaluated by the U.S. Food and Drug Administration (FDA). None of the statements herein, nor any of the products offered, are intended to diagnose, treat, cure, or prevent any medical condition.
All products are supplied strictly as laboratory research reagents and are not for human consumption. We do not provide products to patients and do not make any claims regarding medical use.
Coffee & Pepper Peptides operates solely as a chemical supplier. It is not a compounding pharmacy and does not operate as a compounding facility under Section 503A of the Federal Food, Drug, and Cosmetic Act.
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