Selank — Tuftsin-Based Heptapeptide for Neuropharmacological Research
Selank is a synthetic heptapeptide created by coupling the sequence of the endogenous tetrapeptide tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro stabilizing sequence at the C-terminus. This structural design was conceived to enhance the metabolic stability of the tuftsin core while preserving its biological activity for use in research applications investigating neuropeptide signaling and neuroimmune interactions. Selank has been the subject of extensive investigation in neuropharmacological research, with published studies examining its effects on gene expression profiles in the central nervous system.
In vitro studies using neuronal cell cultures have demonstrated that Selank exposure modulates the expression of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and their respective receptor tyrosine kinases (TrkB and TrkA), suggesting a role in neurotrophic signaling pathway research. Researchers have also investigated the influence of Selank on the expression of genes encoding enkephalin-degrading enzymes and components of the GABAergic and serotonergic neurotransmitter systems, indicating relevance to studies at the intersection of neuroimmunology and neuropeptide biology. The favorable stability profile of Selank makes it a practical tool for extended in vitro experimentation.
Coffee & Pepper Peptides supplies Selank as a research-grade lyophilized peptide with full analytical documentation. This product is for scientific research only and is not intended for human or veterinary use or any clinical application.
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All products are supplied strictly as laboratory research reagents and are not for human consumption. We do not provide products to patients and do not make any claims regarding medical use.
Coffee & Pepper Peptides operates solely as a chemical supplier. It is not a compounding pharmacy and does not operate as a compounding facility under Section 503A of the Federal Food, Drug, and Cosmetic Act.
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