5-AMINO Kit (10 Vials)

5-AMINO-1MQ — Selective NNMT Inhibitor for Metabolic Research

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule research compound that functions as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme extensively studied for its involvement in cellular energy regulation and metabolic pathway modulation. In laboratory settings, this reagent has been utilized to investigate the role of NNMT in NAD+ salvage pathways, methionine metabolism, and stem cell differentiation cascades. Published in vitro data demonstrate that NNMT inhibition by 5-Amino-1MQ produces measurable changes in lipogenic gene expression profiles when applied to adipocyte cell cultures, highlighting the significance of this target in metabolic biochemistry research.

Researchers examining skeletal muscle cell metabolism, epigenetic methylation events, and cellular bioenergetic processes have adopted this compound as a practical and targeted molecular probe. The selectivity of 5-Amino-1MQ for NNMT over other methyltransferase enzymes renders it especially useful in pathway-specific studies where off-target activity must be minimized. Current academic interest centers on the ability of this compound to modulate the interplay between one-carbon metabolism and energy homeostasis signaling networks in mammalian cell types including adipocytes, hepatocytes, and myocytes.

Each vial from Coffee & Pepper Peptides contains research-grade 5-Amino-1MQ, synthesized under stringent quality controls and accompanied by a certificate of analysis verifying identity, purity (≥98% by HPLC), and molecular weight. This product is intended exclusively for qualified researchers in controlled laboratory environments and is not intended for human or veterinary use.

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The information provided on this website has not been evaluated by the U.S. Food and Drug Administration (FDA). None of the statements herein, nor any of the products offered, are intended to diagnose, treat, cure, or prevent any medical condition.

All products are supplied strictly as laboratory research reagents and are not for human consumption. We do not provide products to patients and do not make any claims regarding medical use.

Coffee & Pepper Peptides operates solely as a chemical supplier. It is not a compounding pharmacy and does not operate as a compounding facility under Section 503A of the Federal Food, Drug, and Cosmetic Act.