IPAMORELIN 10MG

Ipamorelin — Selective Growth Hormone Secretagogue Receptor Agonist

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively activates the growth hormone secretagogue receptor type 1a (GHS-R1a), also known as the ghrelin receptor. Distinguished from earlier secretagogue compounds by its high receptor selectivity and minimal off-target activity, Ipamorelin does not significantly stimulate the release of cortisol, prolactin, or aldosterone at research-relevant concentrations — a property that has made it the preferred GHS-R agonist for controlled in vitro studies of somatotroph function and neuroendocrine signaling mechanisms.

The amino acid sequence of Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2) incorporates non-natural amino acids that confer resistance to proteolytic degradation and enhance binding affinity for the GHS-R1a receptor. In cell-based assays, Ipamorelin stimulates intracellular calcium mobilization through Gq-protein coupling, activates the IP3 signaling pathway, and promotes growth hormone release from pituitary somatotroph cell models. Researchers have also used Ipamorelin to study constitutive activity of the GHS-R1a receptor, its interaction with melanocortin receptor systems, and its role in neuroendocrine signaling networks governing energy balance and metabolic homeostasis.

Each vial contains research-grade Ipamorelin, lyophilized for stability and verified for purity by HPLC and identity by ESI-MS. Coffee & Pepper Peptides supplies this peptide exclusively for scientific research purposes. It is not intended for human consumption or any therapeutic use.

FDA DISCLAIMER

The information provided on this website has not been evaluated by the U.S. Food and Drug Administration (FDA). None of the statements herein, nor any of the products offered, are intended to diagnose, treat, cure, or prevent any medical condition.

All products are supplied strictly as laboratory research reagents and are not for human consumption. We do not provide products to patients and do not make any claims regarding medical use.

Coffee & Pepper Peptides operates solely as a chemical supplier. It is not a compounding pharmacy and does not operate as a compounding facility under Section 503A of the Federal Food, Drug, and Cosmetic Act.